Road Trips From San Antonio

Road Trips From San Antonio

Find unforgettable drives from San Antonio. From quick day trips to long adventures, this page lists the most popular road trips starting in San Antonio. Filter by duration, season, direction, and theme to find the perfect route.

38 Curated itineraries
8 Duration options
Updated November 26, 2025

Disclaimer: Details may change without notice. Please verify road conditions, entry requirements, and hours before traveling. RoadTrips is not liable for outdated or incorrect information.

Route map from San Antonio to Twisted Sisters Loop
Day Trip Hard

Twisted Sisters Loop

Texas
View on map

Highlights

FM 335/336/337 legendary motorcycle loop

Route

San Antonio Ranch to Market Rd 335

Driving stats

209 km 2 hrs

Trip profile

Direction NW Score 95

Best months

TBA

Themes

No tags yet

Route map from San Antonio to FM 337 (Medina–Leakey)
Day Trip Medium

FM 337 (Medina–Leakey)

Texas
View on map

Highlights

Twisty climbs & panoramas

Route

San Antonio Salado Balch Springs Little Rock Memphis Louisville Cincinnati Columbus Medina

Driving stats

2296 km 20.9 hrs

Trip profile

Direction NW Score 92

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Willow City Loop
Day Trip Easy

Willow City Loop

Texas
View on map

Highlights

Bluebonnets & Hill Country canyons

Route

San Antonio Comfort Fredericksburg Willow City Loop

Driving stats

145 km 1.6 hrs

Trip profile

Direction NW Score 90

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Highway 16 Bandera–Kerrville
Day Trip Easy

Highway 16 Bandera–Kerrville

Texas
View on map

Highlights

Cowboy culture & mountain curves

Route

San Antonio Kerrville TX-16 & Bandera Hwy

Driving stats

107 km 1.1 hrs

Trip profile

Direction NW Score 88

Best months

TBA

Themes

No tags yet

Route map from San Antonio to River Road (Guadalupe)
Day Trip Easy

River Road (Guadalupe)

Texas
View on map

Highlights

Guadalupe River curves under cypress trees

Route

San Antonio River Rd

Driving stats

52 km 0.6 hrs

Trip profile

Direction NE Score 85

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Missions Trail
Day Trip Easy

Missions Trail

Texas
View on map

Highlights

Mission Concepción, San José, San Juan, Espada

Route

San Antonio Mission Hike and Bike Trails

Driving stats

11 km 0.3 hrs

Trip profile

Direction S Score 85

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Scenic Loop
Day Trip Easy

Scenic Loop

Texas
View on map

Highlights

Hill Country vistas along Scenic Loop

Route

San Antonio Scenic Loop Rd

Driving stats

38 km 0.5 hrs

Trip profile

Direction NW Score 85

Best months

TBA

Themes

No tags yet

Route map from San Antonio to San Antonio Loop Around
Day Trip Easy

San Antonio Loop Around

Texas
View on map

Highlights

Rolling hills and tree tunnels near Helotes

Route

San Antonio Loop St

Driving stats

3 km 0.1 hrs

Trip profile

Direction W Score 80

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Medina Lake
Day Trip Easy

Medina Lake

Texas
View on map

Highlights

Lake views & ranch roads

Route

San Antonio Lakehills Medina Lake

Driving stats

72 km 1 hrs

Trip profile

Direction W Score 78

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Del Rio Secluded Desert Loop
Day Trip Easy

Del Rio Secluded Desert Loop

Texas
View on map

Highlights

Desert plains & Lake Amistad views

Route

San Antonio Del Rio

Driving stats

252 km 2.6 hrs

Trip profile

Direction SW Score 75

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Purgatory Road Loop
Day Trip Easy

Purgatory Road Loop

Texas
View on map

Highlights

San Marcos countryside & Purgatory Road

Route

San Antonio Seguin Ridgefield New York Greenwich Purgatory Rd

Driving stats

3223 km 29.7 hrs

Trip profile

Direction NE Score 70

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Bulverde Loop
Day Trip Easy

Bulverde Loop

Texas
View on map

Highlights

FM 1863 & Hill Country ranch roads

Route

San Antonio Bulverde

Driving stats

50 km 0.6 hrs

Trip profile

Direction N Score 70

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Texas Pig Path
Day Trip Easy

Texas Pig Path

Texas
View on map

Highlights

Quiet Valley Ranch, Guadalupe River

Route

San Antonio Texas

Driving stats

357 km 3.4 hrs

Trip profile

Direction W Score 65

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Floresville Loop
Day Trip Easy

Floresville Loop

Texas
View on map

Highlights

Peanut farms & quiet country highways

Route

San Antonio Floresville

Driving stats

49 km 0.7 hrs

Trip profile

Direction SE Score 60

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Austin
Weekend Easy

Austin

Texas
View on map

Highlights

Live music & downtown culture

Route

San Antonio Austin

Driving stats

128 km 1.4 hrs

Trip profile

Direction NE Score 98

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Fredericksburg
Weekend Easy

Fredericksburg

Texas
View on map

Highlights

Main Street, wineries, Enchanted Rock

Route

San Antonio Comfort Fredericksburg

Driving stats

113 km 1.2 hrs

Trip profile

Direction NW Score 95

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Lockhart
Weekend Easy

Lockhart

Texas
View on map

Highlights

Famous Texas BBQ capital

Route

San Antonio Seguin Lockhart

Driving stats

116 km 1.2 hrs

Trip profile

Direction NE Score 95

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Port Aransas
Weekend Easy

Port Aransas

Texas
View on map

Highlights

Mustang Island beaches

Route

San Antonio Corpus Christi Port Aransas

Driving stats

287 km 2.7 hrs

Trip profile

Direction SE Score 92

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Corpus Christi
Weekend Easy

Corpus Christi

Texas
View on map

Highlights

Beachfront, USS Lexington

Route

San Antonio Corpus Christi

Driving stats

230 km 2.1 hrs

Trip profile

Direction SE Score 90

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Lost Maples
Weekend Medium

Lost Maples

Texas
View on map

Highlights

Fall foliage & canyon trails

Route

San Antonio Bandera Lost Maples State Natural Area

Driving stats

145 km 1.7 hrs

Trip profile

Direction NW Score 88

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Luckenbach
Weekend Easy

Luckenbach

Texas
View on map

Highlights

Famous dance hall & country music

Route

San Antonio Boerne Luckenbach

Driving stats

100 km 1.1 hrs

Trip profile

Direction NW Score 85

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Pedernales Falls
Weekend Easy

Pedernales Falls

Texas
View on map

Highlights

Pedernales Falls scenic overlooks

Route

San Antonio Pedernales Falls State Park

Driving stats

123 km 1.4 hrs

Trip profile

Direction N Score 85

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Kerrville
Weekend Easy

Kerrville

Texas
View on map

Highlights

Guadalupe River parks

Route

San Antonio Kerrville

Driving stats

105 km 1.1 hrs

Trip profile

Direction NW Score 82

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Wimberley
Weekend Easy

Wimberley

Texas
View on map

Highlights

Blue Hole & scenic shops

Route

San Antonio San Marcos Wimberley

Driving stats

101 km 1.1 hrs

Trip profile

Direction NE Score 80

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Brenham
Weekend Easy

Brenham

Texas
View on map

Highlights

Blue Bell Creamery

Route

San Antonio Seguin Flatonia La Grange Brenham

Driving stats

240 km 2.5 hrs

Trip profile

Direction NE Score 80

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Bandera
Weekend Easy

Bandera

Texas
View on map

Highlights

Cowboy Capital of the World

Route

San Antonio Bandera

Driving stats

82 km 1 hrs

Trip profile

Direction W Score 80

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Dripping Springs
Weekend Easy

Dripping Springs

Texas
View on map

Highlights

Hamilton Pool & breweries

Route

San Antonio Blanco Dripping Springs

Driving stats

120 km 1.4 hrs

Trip profile

Direction N Score 78

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Blanco
Weekend Easy

Blanco

Texas
View on map

Highlights

Lavender farms & Blanco State Park

Route

San Antonio Blanco

Driving stats

500 km 5 hrs

Trip profile

Direction N Score 75

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Bastrop
Weekend Easy

Bastrop

Texas
View on map

Highlights

Pine forests & small-town charm

Route

San Antonio Austin Bastrop

Driving stats

169 km 1.7 hrs

Trip profile

Direction NE Score 70

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Round Top
Weekend Easy

Round Top

Texas
View on map

Highlights

Antique fairs & countryside

Route

San Antonio Seguin Flatonia La Grange Round Top

Driving stats

204 km 2.1 hrs

Trip profile

Direction NE Score 70

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Bandera–Kerrville Extended Loop
3–4 Days Easy

Bandera–Kerrville Extended Loop

Texas
View on map

Highlights

Extended Hill Country riding

Route

San Antonio Comfort Bandera Hwy

Driving stats

103 km 1.1 hrs

Trip profile

Direction NW Score 70

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Big Bend National Park
5–7 Days Medium

Big Bend National Park

Texas
View on map

Highlights

Chisos Basin, Santa Elena Canyon

Route

San Antonio Alpine Big Bend National Park

Driving stats

737 km 6.6 hrs

Trip profile

Direction W Score 98

Best months

TBA

Themes

No tags yet

Route map from San Antonio to South Padre Island Loop
5–7 Days Easy

South Padre Island Loop

Texas
View on map

Highlights

Island beaches & Gulf drives

Route

San Antonio Brownsville Port Isabel South Padre Island

Driving stats

479 km 4.5 hrs

Trip profile

Direction S Score 95

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Big Bend/Terlingua/Marfa Loop
5–7 Days Medium

Big Bend/Terlingua/Marfa Loop

Texas
View on map

Highlights

Marfa lights, Big Bend desert roads

Route

San Antonio Alpine Study Butte Terlingua

Driving stats

739 km 6.6 hrs

Trip profile

Direction W Score 90

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Mexico City
10–15 Days Hard

Mexico City

Mexico
View on map

Highlights

Mountain highways & Mexican inland cities

Route

San Antonio Nuevo Laredo Naucalpan de Juárez Mexico City

Driving stats

1378 km 15.4 hrs

Trip profile

Direction S Score 88

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Banff
15–20 Days Hard

Banff

Canada
View on map

Highlights

Icefields Parkway & Rockies

Route

San Antonio Ballinger Slaton Amarillo Banff

Driving stats

3353 km 30.8 hrs

Trip profile

Direction N Score 90

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Vancouver
30–45 Days Hard

Vancouver

Canada
View on map

Highlights

Cascades, British Columbia coastline

Route

San Antonio Eden Roswell Farmington Salt Lake City Bellevue Vancouver

Driving stats

3681 km 34.6 hrs

Trip profile

Direction NW Score 85

Best months

TBA

Themes

No tags yet

Route map from San Antonio to Alaska Highway
45–60 Days Hard

Alaska Highway

Alaska
View on map

Highlights

Yukon, wilderness, Alaska Highway

Route

San Antonio Plainview Alaska Hwy

Driving stats

5635 km 54.4 hrs

Trip profile

Direction NW Score 92

Best months

TBA

Themes

No tags yet